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| Section | Weight | Objectives |
|---|---|---|
| Healthcare Systems and Population Health | 10% | - Population-based pharmacotherapy - Regulatory and economic considerations - Healthcare delivery models - Medication safety and quality improvement |
| Patient-Centered Pharmacotherapy | 65% | - Pathophysiology and clinical presentation - Pharmacokinetics and pharmacodynamics - Adverse drug reactions and interactions - Drug selection, dosing, and monitoring - Therapeutic guidelines and evidence-based treatment |
| Application of Evidence to Practice and Education | 25% | - Clinical research and guideline development - Patient education and counseling - Drug information and communication - Literature evaluation and biostatistics |
1. A 59-year-old patient with a diagnosis of deep vein thrombosis is anticoagulated with enoxaparin 1 mg/kg every 12 hours and warfarin 5 mg daily. On the third day of therapy, his INR
= 2.2. The patient is symptomatically improved. Which of the following is the most appropriate management of this patient?
A) Continue enoxaparin and warfarin.
B) Discontinue enoxaparin and continue warfarin.
C) Discontinue enoxaparin and increase warfarin.
D) Continue enoxaparin and hold Warfarin.
2. A 58-year-old man presents with symptoms of the common cold (nasal congestion, headaches, and dry Cough).
He purchased XYZ Cold formula (acetaminophen, pseudoephedrine, and dextromethorphan), but after reading the cautionary information on the package, he thought he should obtain his pharmacist's advice. He has hypertension and is taking hydrochlorothiazide daily. His office blood pressures range from 127-134/82-88 mm Hg, and he has no other medical problems.
Which of the following instructions are applicable to this patient regarding XYZ Cold formula?
A) He should substitute nasal cromolyn for the decongestant.
B) Although pseudoephedrine is safe to use, he should use an antihistamine instead to better control his symptoms.
C) He should avoid XYZ Cold because it significantly raises blood pressure.
D) XYZ Cold would be safe short term because he has well-controlled hypertension.
3. A 74-year-old man has been diagnosed with acute bacterial prostatitis. He has no known drug allergies. Which of the following is the optimal therapy duration with levofloxacin 500 mg daily?
A) 6-8 Weeks
B) 3-5 days
C) 2-4 Weeks
D) 7-10 days
4. A 66-year-old man with a history of chronic bronchitis is seen in October for treatment of an acute exacerbation. He received the pneumococcal vaccine 3 years ago and an influenza vaccine this past March. Which of the following should the pharmacotherapy specialist recommend?
A) Influenza Vaccine
B) Oseltamivir With influenza Vaccine
C) Neither Vaccine
D) Both Vaccines
5. A pharmacotherapy specialist is evaluating a study that compared the effects of iron sucrose versus sodium ferric gluconate on ferritin levels in patients receiving hemodialysis. A significant difference was found between the groups. This study was conducted in a large academic center in Denmark; the specialist practices at a small rural hospital in Minnesota. Which of the following information in the paper will be most important in determining whether the study's results can be applied to the specialist's practice?
A) Inclusion/exclusion criteria
B) Statistical analysis
C) Randomization methods
D) Internal validity
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: D | Question # 3 Answer: C | Question # 4 Answer: C | Question # 5 Answer: A |
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